https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Post-traumatic stress disorder affects fucose-alpha(1-2)-glycans in the human brain: preliminary findings of neuro deregulation using in vivo two-dimensional neuro MR spectroscopy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47742 n = 10) were compared with PTSD participants with minimal co-morbidities (n = 10). The 2D MRS identified statistically significant increases in the total spectral region containing both free substrate fucose and fucosylated glycans of 31% (P = 0.0013), two of multiple fucosylated glycans (Fuc IV and VI) were elevated by 48% (P = 0.002), and 41% (P = 0.02), respectively, imidazole was increased by 12% (P = 0.002), and lipid saturation was increased by 12.5% (P = 0.009). This is the first evidence of fucosylated glycans, reported in animals to be involved in learning and memory, to be affected in humans with PTSD.]]> Wed 25 Jan 2023 15:28:52 AEDT ]]> Lipid and metabolite deregulation in BRCA1 and BRCA2 genetic mutations: response https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24236 Wed 16 Nov 2016 14:36:47 AEDT ]]> Lipid and metabolite deregulation in the breast tissue of women carrying BRCA1 and BRCA2 genetic mutations https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27597 Sat 24 Mar 2018 07:25:17 AEDT ]]>